First, the virus must get inside the cell. Every virus does this slightly differently, but most use their signature “spikes” to fuse themselves to a cell’s outer membrane and then squeeze their way inside.
Tollovid + Rebounders
Exploring Viral Persistence after a paxlovid rebound
We're excited to learn how Tollovid is positively impacting those suffering from ongoing PASC symptoms after experiencing a Paxlovid Rebound.
Rebounding is when a patient who, after receiving a full five-day course of Paxlovid treatment, either has a reemergence of COVID symptoms or tests positive after a previous, negative test. Patients with evidence of persistent virus expression went on to develop conditions typical of long Covid, including brain fog, fatigue, and loss of smell.
WHAT IS A PAXLOVID REBOUND?
HOW DOES TOLLOVID HELP?
Observational Study Data: Key Highlights
Case Study Data: April - June 20, 2022 n = 41
of Acute COVID-19 respondents reported
a decrease in Acute COVID Symptoms.
of Long COVID (0-6 months) respondents reported a decrease in Long COVID Symptoms.
of Long COVID (0-9 months) respondents reported a decrease in Long COVID Symptoms.
of Acute COVID-19 respondents reported that they were happy with their results with Tollovid.
of Long COVID (0-6 months) respondents reported that they were happy with their results.
of Long COVID (0-9 months) respondents reported that they were happy with their results.
A Case Study of Paxlovid Rebound Patient
“As of three days ago all her symptoms were resolved. She attributes this recovery to the treatment with Tollovid."
Symptoms Include: Fatigue, Tinnitus, Insomnia, Brain Fog, Fever, Joint Pain, Gastrointestinal Issues, Shortness of Breath, and Changes in Libido
How Tollovid™ Works:
1. Binding & Entry
Once inside, the virus RNA instructs the cell to make a long polypeptide containing special enzymes. This long protein must be cut apart for the virus to replicate. To accomplish this, the virus encodes a special ‘scissors’, called 3CL protease, which cuts up the polypeptide into the different enzymes that then become functional.
Before these enzymes can start working, they need to be separated from each other. The protease enzyme acts like a pair of scissors, cutting the polypeptide up into the different enzymes that then become functional.
4. 3CL Protease Inhibitors
Protease inhibitors, like Tollovid, are designed to tightly bind to the protease enzyme, blocking its ability to cut. This shuts down the entire virus-making apparatus, leaving it unable to make a single virus.