Tollovid + Long COVID*

Exploring Viral Persistence in PASC

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Tollovid has shown to positively impact those with PASC* symptoms.

Long COVID is impacting millions of people. If you have long term effects related to COVID, you’re not alone. Tollovid™ is committed to finding answers. Our research team is working to learn more about the long-term effects of COVID so we can try to help.

ONGOING MARKET RESEARCH STUDY

We are compiling 100+ individual case studies with PASC participants as their physicians monitor their symptoms and progress on Tollovid™ over 30, 60, and 90 day periods.

UPCOMING CLINICAL STUDIES

We are also conducting a randomized, observer blinded, non-exposure control study to evaluate the safety of Tollovid™ and it’s effects on the structure/function of the immune system in subjects with Long COVID.

What is Long COVID?

Building Our Understanding of Recovery:

Long COVID, or post-acute sequelae of COVID-19 (PASC), is a condition marked by the continuation of COVID-19 symptoms—or the emergence of new ones—after recovery from acute COVID-19. It generally refers to the persistence of symptoms four weeks or longer after the onset of COVID-19.

About PASC Symptoms:

Long-term effects of COVID can be different for everyone and they can affect many different parts of the body, such as the heart, brain, and lungs. And people who have PASC, including Long COVID, can have different kinds of effects. These effects may come and go, and they may last for a few weeks, a few months, or longer.


What Long COVID Symptoms** Are You Experiencing?

**This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Fatigue

71.4%

of IRB-Waived Survey Respondents reported
a decrease in fatigue after taking Tollovid.


Post-viral fatigue is when you have an extended period of feeling unwell and fatigued after a viral infection. Fatigue is a normal part of the body’s response to fighting a viral infection such as COVID-19. Fatigue is likely to continue for some time after the infection has cleared. It can make you sleep more, feel unsteady on your feet, make standing for long periods difficult, as well as affecting your ability to concentrate and your memory.

Shortness of Breath

73.9%

of IRB-Waived Survey Respondents reported
a decrease in shortness of breath.


Infections and viruses can significantly impact the respiratory system. Many patients suffer the effects of lung damage during an acute infection, including shortness of breath and coughing. This is likely due to a combination of the body’s exaggerated immune system reaction to the virus and blood clots that obstruct oxygen intake in the lungs. Fortunately, the symptom is usually short-lived.

For patients who go on to develop Long COVID, however, this may become a long-term symptom affecting quality of life. There’s limited research so far, but shortness of breath may be linked to interference with brain blood flow or problems related to the autonomic nervous system. As a result, many Long COVID patients have a dysfunctional breathing pattern.

COUGH

81%

of IRB-Waived Survey Respondents reported
a decrease in coughing with Tollovid.


Coughing is one of the most common symptoms of COVID-19, and for some people, a lingering cough can persist for months after infection. Studies show that as many as 5 percent of people infected with COVID have a cough lasting four or more weeks.

sensory loss

78.6%

of IRB-Waived Survey Respondents reported
a increase in sensory perception.


"I am going to take another round of Tollovid, because my sense of smell has been returning for longer periods more frequently in the last several weeks. I attribute it to Tollovid because right before I started, I had no taste or smell for 99.99% of the time. Now I am gradually smelling."

- Respondent #1029

headaches

68.5%

of IRB-Waived Survey Respondents reported
a decrease in headaches with Tollovid.


Headache is among the most frequent symptoms persisting or newly developing after COVID-19 as part of the long COVID syndrome. Long COVID headache can present in the form of worsening of a preexisting primary headache, or, more specifically, in the form of a new (intermittent or daily) headache starting during the acute infection or after a delay. It often presents together with other long COVID symptoms, most frequently with hyposmia. It can manifest with a migrainous or, more frequently, with a tension-type-like phenotype. Persistent activation of the immune system and trigeminovascular activation are thought to play a role.

brain fog

73.6%

of IRB-Waived Survey Respondents reported
a decrease in brain fog after taking Tollovid.


"Brain fog has decreased. Overall, I feel better." - Respondent #1096


Among people who were hospitalized for COVID, a wide range of problems with cognition have been reported. People struggling with the effects of long COVID may have noticeable problems with attention, memory, and executive function. Studies report these issues both in people who were not hospitalized with COVID and in those who were, as well as in people who had severe cases. Those who tried Tollovid reported benefits in their brain fog symptoms.

Tachycardia + heart rate issues

61.3%

of IRB-Waived Survey Respondents reported
a decrease in heart issues with Tollovid.


Although COVID-19 is primarily a respiratory or lung disease, the heart can also suffer. As the virus causes inflammation and fluid to fill up the air sacs in the lungs, less oxygen can reach the bloodstream. The heart has to work harder to pump blood through the body, which can be dangerous in people withpreexisting heart disease. The infection may infect and damage the heart’s muscle tissue directly, as is possible with other viral infections, including some strains of the flu. Coronavirus infection also affects the inner surfaces of veins and arteries, which can cause blood vessel inflammation, damage to very small vessels and blood clots, all of which can compromise blood flow to the heart or other parts of the body.

Viral infections can cause cardiomyopathy, a heart muscle disorder that affects the heart’s ability to pump blood effectively. When attacked by a virus, the body undergoes stress and releases a surge of chemicals called catecholamines, which can stun the heart. Once the infection resolves, the stressor has ended and the heart can recover.

Gastrointestinal issues

45.5%

of IRB-Waived Survey Respondents reported
an improvement in GI function.


Acute COVID-19 is associated with gastrointestinal symptoms such as nausea, vomiting, diarrhoea and abdominal pain. In patients with PACS, gastrointestinal-related symptoms includes loss of appetite, nausea, weight loss, abdominal pain, heartburn, dysphagia, altered bowel motility and irritable bowel syndrome. Emerging evidence demonstrates persistent and aberrant inflammationas well as induction of autoimmunity in a subset of patients with PASC.  Viral persistence beyond acute COVID-19 has also been documented withinmultiple organs, including the gastrointestinal tract and centralnervous system. 

Key Data: Our IRB-Waived Study**

April - August 19, 2022 n = 104

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. **Please note that our studies are still ongoing.

94%

of Acute Infection respondents reported a decrease in symptoms.


90%

of Long COVID (0-6 months) respondents reported a decrease in symptoms.
.

81%

of Long COVID (0-9 months) respondents reported a decrease in symptoms.

95%

of Acute Infection respondents reported they were happy with their results with Tollovid.


80%

of Long COVID (0-6 months) respondents reported they were happy with their results.


67%

of Long COVID (0-9 months) respondents reported they were happy with their results.


Case Studies: Key Highlights

CASE STUDY 1

Long COVID Patient with Fatigue Reports Benefits from Tollovid®

“All of her symptoms were eliminated within 1 week. At the end of the week she tested negative by PCR.”

Symptoms Include: Fatigue, Insomnia, Headaches, and Joint Pain

CASE STUDY 2

Long COVID Patient with ED Sees Resolution with Tollovid®

“After 3 days, his fatigue subsided, his memory improved, the joint pain dissipated, and his erectile dysfunction was resolved.”

Symptoms Include: Fatigue, Insomnia, Brain Fog, Joint Pain, Dizziness, and Erectile Dysfunction

CASE STUDY 3

Paxlovid Rebounder with Brain Fog Sees Benefits with Tollovid®

“As of three days ago all her symptoms were resolved. She attributes this recovery to the treatment with Tollovid.

Symptoms Include: Fatigue, Tinnitus, Insomnia, Brain Fog, Fever, Joint Pain, Gastrointestinal Issues, Shortness of Breath, and Changes in Libido

CASE STUDY 4

Long COVID Patient with Cardiovascular Issues Sees Improvement

“After taking Tollovid, my flare-ups are less intense with a rating of only 3 out of 10. Because of Tollovid, I am suffering less now.”

Symptoms Include: Fatigue, Insomnia, Heart Palpitations, Gastrointestinal Issues, Brain Fog, and Vision Issues

CASE STUDY 5

PASC Patient with Erectile Dysfunction Sees Benefit with Tollovid®

“Tollovid has gotten me back to 85% of my pre-COVID state. No other intervention I’ve tried so far has been able to do that.”

Symptoms Include: Fatigue, Joint Pain, Pins & Needles, Headache, Anxiety, Insomnia, Gastrointestinal Issues, Urinary Issues, and Erectile Dysfunction

CASE STUDY 6

PASC Patient with Cardiovascular Issues Sees Benefits with Tollovid®

“After 5 days of restarting Tollovid, I have recovered to 85%. I can run for 30 minutes, and my resting heart rate is back down to 60 bpm.”

Symptoms Include: Fatigue, Headache, Anxiety, Insomnia, Breathing Issues, and Heart Palpitations

CASE STUDY 7

Acute & Long COVID Patient Sees Resolution with Tollovid®

“She took 12 Tollovid capsules daily for 5 days, and saw her symptoms completely resolve in 3 – 4 days.”

Symptoms Include: Fatigue, Joint Pain, Fever, Clammy Hands, and Vision Issues

CASE STUDY 8

Pax Rebound & PASC Patient Sees Benefit with Tollovid®

“I now feel better than I have in the past 27 months”

Symptoms Include: Fatigue, Pins and Needles, Sensory Loss, Gastrointestinal Issues, Shortness of Breath, and Tachycardia

CASE STUDY 9

Long COVID Patient with Microclots Who Benefitted From Tollovid®

"Tollovid helped improve my cognitive impairment, a symptom that was severely impacting my quality of life. Alongside the triple anti-coagulation therapy, Tollovid has helped improve the overall trajectory of my recovery from Long Covid."

Symptoms Include: Loss of Taste and Smell, Fevers, Headaches, Body Aches, Fatigue, Cognitive Decline, Sleep Disturbance, Brain Fog, Elevated Heart Rate

How Tollovid™ Works:

1. Binding & Entry

First, the infection must get inside the cell. Every infection does this slightly differently, but most use their signature “spikes” to fuse themselves to a cell’s outer membrane and then squeeze their way inside.

2. POLYPEPTIDES

Once inside, the RNA instructs the cell to make a long polypeptide containing special enzymes. This long protein must be cut apart for the infection to replicate. To accomplish this, the infection encodes a special ‘scissors’, called 3CL protease, which cuts up the polypeptide into the different enzymes that then become functional.

3. Replication

Before these enzymes can start working, they need to be separated from each other. The protease enzyme acts like a pair of scissors, cutting the polypeptide up into the different enzymes that then become functional.

4. 3CL Protease Inhibitors

3CL Protease Inhibitors, like Tollovid, are designed to tightly bind to the protease enzyme, blocking its ability to cut. This shuts down the entire infection-cloning apparatus, leaving it unable to replicate.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

More Rave Reviews

Recommended Regimen

3

capsules

4

times per day

15+

days duration

How many bottles do I need?

For Long COVID, we recommend 3-4 bottles depending on the severity of your symptoms.

$204.00

Stay updated on the latest Long COVID news, research, and resources: